In your dreams at night, do you see a place filled with color, culture, and jaw-dropping scenery? It’s likely that place is Latin America. The entire region is bursting with colorful cities that are as vibrant as they are beautiful – from colonial charmers to modern hubs surrounded by nature.
If Latin America’s been calling your name, you should definitely answer. And, to help you start planning, we’ve rounded up ten of the most stunning cities – five popular hotspots that are well-loved and five under-the-radar treasures that you might not know about (yet).
Whether you love historic streets, mountain views, or just a good plate of empanadas, there’s something on this list that will sweep you away and steal your heart forever.
Cartagena, Colombia
Cartagena is one of those cities that feels like stepping into a fairytale. Imagine pastel-colored houses, bougainvillea-draped balconies, and cobbled streets surrounded by centuries-old walls. Founded in 1533, this port city played a huge role in the Spanish empire, and it has the forts and churches to prove it.
When you’re here, wander around the walled Old City, pop into little cafés for fresh arepas, and see the Castillo San Felipe de Barajas – a fortress with fantastic views. If the sun gets too hot, all you have to do is hop on a boat to the nearby Rosario Islands for white-sand beaches and crystal-clear water. It’s touristy, yes, but for good reason. Cartagena is romantic, lively, and absolutely unforgettable.
Buenos Aires, Argentina
Buenos Aires is often called the “Paris of South America” and, honestly, it lives up to the name. With its elegant architecture, leafy boulevards, and passionate tango culture, the city is incredibly charming. It’s a fiery mix of European sophistication and Latin soul.
Each neighborhood has its own flavor. San Telmo is all cobblestones and antiques, while Palermo is full of trendy boutiques and street art. Don’t miss the colorful houses of La Boca or a tour of the historic Teatro Colón. And, of course, don’t leave without savoring a steak dinner and a tango show. Or, better yet, join a class yourself. Where better to pick up a few pointers?
Rio de Janeiro, Brazil
There’s nowhere in the world quite like Rio. It’s a city of dramatic contrasts. Mountains, jungles, and the sea all collide here in the most spectacular way. Add in some samba music and those golden beaches, and it’s easy to see why it’s so iconic.
Yes, you’ll want to see all the important things: Christ the Redeemer, Sugarloaf Mountain, and Copacabana Beach. But, there’s more to it than that. Hike in Tijuca National Park for a glimpse of all the wildlife and waterfalls. Then, visit the bohemian Santa Teresa neighborhood with its steep hills and art studios. Rio is bold, beautiful, and completely alive.
Cusco, Peru
Before you race off to Machu Picchu (which you definitely should), take time to explore Cusco. Once the capital of the Inca Empire, this city blends ancient and colonial history in the most beautiful way. Stone walls from Incan times still stand alongside Spanish cathedrals and markets.
Stroll through the Plaza de Armas, visit the majestic Qorikancha temple, and sample the local cuisine. The San Pedro Market is a sensory overload in a most magnificent way. And, while Cusco is a gateway to the Sacred Valley, the city itself deserves more than a quick overnight stay.
Mexico City, Mexico
Mexico City might be one of the most underrated capital cities in the world. It’s massive, yes, but packed with color, creativity, and culture. The city dates back to the Aztecs and is now a dynamic blend of old and new.
Visit the historic center to see the Zócalo, the Templo Mayor ruins, and the grand Palacio de Bellas Artes. Then, head to neighborhoods like Roma and Condesa for leafy streets, art galleries, and top-notch food.
Don’t miss Frida Kahlo’s house in Coyoacán or a boat ride in the canals of Xochimilco. CDMX is buzzing with energy and, once you’re here, you’ll wonder why you didn’t visit sooner. And, if it pulls on your heart string the way we think it will, come check out 15 additional destinations in Mexico most Americans don’t know about.
Cuenca, Ecuador
Now for some of the smaller gems. Cuenca is a city that surprises you. It’s a UNESCO World Heritage Site full of colonial charm, red-tiled roofs, and flower-filled plazas. The city was built on the ruins of a Cañari settlement and later became an important stop during the Spanish colonization.
You can walk along the Rio Tomebamba, explore the stunning Catedral Nueva, and spend a quiet afternoon at the Pumapungo ruins and museum. Cuenca is a big expat hub, but it still feels calm and local. It’s the kind of place where time slows down, which is perfect if you’re looking for somewhere beautiful but not too overwhelming.
Valparaíso, Chile
If you love street art, ocean views, and cities that feel like living art projects, Valparaíso is for you. Once one of the most important ports on the Pacific, this city has reinvented itself as Chile’s artsy, slightly scrappy coastal gem.
Colorful houses cling to the hillsides, connected by winding staircases and old funiculars. Be sure to explore Cerro Alegre and Cerro Concepción for cafes, murals, and panoramic views. There’s also a strong literary history here. Poet Pablo Neruda had a home here and it’s now a quirky museum. Valparaíso is not your typical beach town, but that’s what makes it so special.
Granada, Nicaragua
Granada is one of Central America’s oldest cities, founded by the Spanish in 1524, and it shows in the architecture. Picture bright yellow churches, horse-drawn carriages, and palm trees swaying in the breeze. It’s pretty as a picture, and still very relaxed and easygoing.
You can explore the colonial core in an afternoon, but there’s more nearby: take a boat tour through Las Isletas on Lake Nicaragua, hike around Mombacho Volcano, and visit local markets. Granada is affordable, friendly, and full of old-world charm without the tourist crowds.
Salta, Argentina
Way up in Argentina’s northwest, Salta is surrounded by red rock canyons, Andean peaks, and vineyards. Founded in 1582, it has one of the best-preserved colonial centers in the country, filled with elegant buildings, lively plazas, and some seriously good empanadas.
Hop on the Tren a las Nubes (Train to the Clouds) for an unforgettable ride through the mountains, or rent a car and drive the stunning Route 68 to Cafayate. It’s like a less-discovered Mendoza, with fewer tourists but just as much wine and scenery. If you love landscapes and authenticity, then Salta is your beginning, middle, and end.
Suchitoto, El Salvador
Suchitoto is one of El Salvador’s best-kept secrets. Set in the hills overlooking Lake Suchitlán, it’s full of colonial buildings, cobbled streets, and art galleries. The town was heavily affected by the country’s civil war, but has reinvented itself as a peaceful and creative hub.
Stop by the stoic whitewashed church in the main square, hike to the waterfalls, and take a boat ride on the lake. The town also hosts film and arts festivals throughout the year. It’s the kind of place where you can sit with a coffee and just soak it all in – no rush, no stress, just beauty and quiet charm.
Ready to Go?
Whether you’re chasing the energy of a big city or looking for a quiet, picturesque escape, Latin America has a little bit of everything for ya. Some places are popular for a reason, and others are waiting to be discovered. All you have to do is pack light, bring your curiosity, and seek out the kind of beauty that stays with you long after the trip is over.
Come check out our library of destination guides before you go. It’s filled with wonder to help you round out your trip to Latin America, the Caribbean, and beyond. We’re here to help you curate the itinerary or your dreams and hope that, someday, we meet in the sunny streets of Salta.